Extractive Spectrophotometric Method for the Determination of Lamivudine and Zidovudine in Pharmaceutical Preparations Using Bromocresol Purple
نویسندگان
چکیده
منابع مشابه
Spectrophotometric Determination of Metronidazole in Pharmaceutical Preparations
A rapid and sensitive spectrophotometric method is proposed for determination of Metronidazole. The method depends on the reduction of Metronidazole molecule with zinc dust and hydrochloric acid flowed by diazotation and coupling with 8-quinolinol to give colored chromogens easily measured spectrophotometrically which has λmax= 437 nm. The experimental conditions were optimized and berr’s law w...
متن کاملSpectrophotometric Determination of Diclofenac in Pharmaceutical Preparations
Neste trabalho é proposto um método espectrofotométrico modificado para a determinação de diclofenaco em preparações farmacêuticas. Usa-se solução de cobre(II) como reagente, o que leva à formação de um complexo cobre(II)-diclofenaco de cor verde, com máximo de absorção em 680 nm. Foram estudadas as influências: do pH; da concentração de cobre(II); do uso de ácido acético na solução de cobre(II...
متن کاملExtractive Spectrophotometric Determination of Mirtazapine in Pure and Pharmaceutical Forms
Four simple and sensitive extractive spectrophotometric methods have been described for the assay of Mirtazapine either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromocresol green (BCG), bromophenol blue (BPB), bromothymol blue (BTB) and bromocresol purple (BCP) in acidic medium....
متن کاملDerivative Spectrophotometric Method for Determination of Losartan in Pharmaceutical Formulations
Losartan, a highly effective blood pressure lowering agent, has been widely used for the treatment of hypertension. A fast and reliable method for the determination of losartan was highly desirable to support formulation screening and quality control. A first derivative UV spectroscopic method was developed for determination of losartan in the tablet dosage form. The first derivative spectrum r...
متن کاملSenSitiVe SPeCtroPHotometriC DeterminAtion oF LAmotrigine in BuLK Drug AnD PHArmACeutiCAL FormuLAtionS uSing BromoCreSoL green
Two new, simple, rapid and reproducible spectrophotometric methods have been developed for the determination of lamotrigine (LMT) both in pure form and in its tablets. The first method (method A) is based on the formation of a colored ion-pair complex (1:1 drug/dye) of LMT with bromocresol green (BCG) at pH 5.02±0.01 and extraction of the complex into dichloromethane followed by the measurement...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Chemistry
سال: 2013
ISSN: 2090-9063,2090-9071
DOI: 10.1155/2013/484389